PCAA

Can Peptide Therapy Help Improve My Seasonal Allergies?

Apr 25, 2025
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Sneezing, itchy eyes, congestion? Seasonal allergies could be to blame, and peptide therapy may help improve them. Read on to learn what peptide therapy is and how it can help you find relief.

If you dread allergy season, you aren’t alone. Millions of people — about one-quarter of American adults — experience frustrating symptoms like sneezing, itchy eyes, congestion, and fatigue as the seasons change. Although over-the-counter medications can offer relief, they don’t always get to the root of the issue or provide lasting improvement. 

The good news? You can try peptide therapy to help with seasonal allergies, too. Here at the Philadelphia Center for Anti-Aging in Philadelphia, Pennsylvania, Stephen Ficchi, DO, offers peptide therapy to help with skin rejuvenation, longevity, weight loss, hair restoration, hormone balance, and allergies!

Peptides are short chains of amino acids that act as messengers in your body, and they help to regulate various biological processes. But how does that help with seasonal allergies? 

Read on to find out.

How seasonal allergies affect your body

When your immune system encounters allergens like pollen, dust, or mold, it can overreact, triggering the release of histamines. Histamines are compounds in your body that trigger allergy symptoms like a runny nose, watery eyes, coughing, and sneezing.

Over time, chronic inflammation can worsen these symptoms and lead to fatigue or even asthma flare-ups. All of that together can leave you feeling not your best.

The science behind peptide therapy and seasonal allergies 

Peptide therapy uses specific peptides to support healing, reduce inflammation, and improve your immune function. Because your immune system plays a central role in allergic reactions, balancing it with targeted peptides may help reduce the severity of seasonal allergy symptoms.

Peptide therapy for allergies has been shown to help people react less strongly to allergens. It works by increasing helpful antibodies (IgG4) and lowering the ones that cause allergic reactions (IgE)

Certain peptides can also reduce hypersensitivity by promoting immune tolerance. For instance, allergen-specific peptide immunotherapy has been shown to induce regulatory T cells and decrease the activity of Th2 cells, which are associated with allergic reactions. Lolium perenne pollen peptides are another type of peptide therapy. This one, in particular, reduced the symptoms of people suffering from grass pollen allergies.

To put it plainly, peptide therapy can help your body stop overreacting to things like pollen or pet dander. It trains your immune system to become more tolerant, which means fewer allergy symptoms like sneezing, itchy eyes, or congestion. Think of it like teaching your body not to panic over harmless things.

What to expect from peptide therapy for seasonal allergies

Peptide therapy may:

  • Support immune system balance
  • Decrease chronic inflammation
  • Improve your body’s ability to tolerate allergens
  • Reduce the frequency or severity of allergy symptoms

In addition to relieving allergy symptoms, peptide therapy offers the benefit of being gentle on your body. The peptides used at Philadelphia Center for Anti-Aging are derived from natural sources, such as hemp seeds, milk, wheat, and eggs.

Because they're naturally occurring and well-tolerated, most people experience little to no side effects. Win-win! 

Is peptide therapy right for you?

Peptide therapy isn’t a one-size-fits-all solution, but if you’re looking for a more holistic and long-term way to manage your seasonal allergies, it may be worth exploring. At Philadelphia Center for Anti-Aging, Dr. Ficchi customizes your peptide therapy to your individual health goals, including allergy support, immune health, and energy optimization.

We’ll review your symptoms, health history, and run any necessary labs to determine which peptides, if any, may be most effective for you.

If seasonal allergies are interfering with your life and you’re ready for a new approach, schedule a consultation with our team.